The drain current flowing through semi-conductor will be determined by electronic density inside of the semi-conductor. The chemical ion change caused by biological reaction such as enzyme reaction will be transferred into semiconductor as electric field change. The electric field change causes polarization in semi-conductor, which change the current flowing through the gate channels.
AMIS sensor stores the signal measured per measurement inside the sensor for amplification to improve S/N ratio, which realized high sensitive and precise measurement, while conventional ISFET sensor cannot achieve because of poor S/N ratio due to small signal.
Possible to detect various kinds of enzymatic reactions in sensitive
And detecting the resulting oleic acid hydrolysis of Olive oil due to the Lipoprotein Lipase
Detection example of Creatinine hydrolysis reaction due to Creatinine Deiminase
Conventional three types of enzymes are required Easily it can be measured in a single enzyme
The features of Micro Bioactivity Analyzer AMIS-101are shown in
Biocatalysis and Agricultural Biotechnology (2012)
